Slc4a9^tm1Doel
Targeted Allele Detail

Summary

• Symbol: Slc4a9^tm1Doel
• Name: solute carrier family 4, sodium bicarbonate cotransporter, member 9; targeted mutation 1, Dominique Eladari
• MGI ID: MGI:5516078
• Gene: Slc4a9 Location: Chr18:36661200-36689326 bp, + strand Genetic Position: Chr18, 19.46 cM
• Alliance: Slc4a9^tm1Doel page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:197347
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Mutation details: A reporter construct with lacZ and neomycin resistance genes replaced the segment between the coding sequence in exon 1 through exon 5. Immunohistochemistry confirmed the absence of protein expression in the kidney. (J:197347)

Generation of the Slc4a9^tm1Doel allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc4a9 Mutation: 37 strains or lines available

References

• Original: J:197347 Chambrey R, et al., Renal intercalated cells are rather energized by a proton than a sodium pump. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7928-33
• All: 1 reference(s)