Gnaq^M1J
Chemically induced Allele Detail

Summary

• Symbol: Gnaq^M1J
• Name: guanine nucleotide binding protein, alpha q polypeptide; mutation 1, Jackson
• MGI ID: MGI:5516345
• Synonyms: Gnaq^T54A
• Gene: Gnaq Location: Chr19:16110195-16364827 bp, + strand Genetic Position: Chr19, 11.01 cM
• Alliance: Gnaq^M1J page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: This ENU-induced mutation has an A to G transition in exon 2, Chromosome 19 position 16,219,611 bp (GRCm38), predicted to cause a threonine to alanine substitution at amino acid 54. (J:231947)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gnaq Mutation: 24 strains or lines available

References

• Original: J:231947 Pratt CH, et al., Gnaq(M1J): An ENU-Induced Mutant Allele Affecting Pigmentation in the Mouse. J Invest Dermatol. 2016 Jan;136(1):334-6
• All: 1 reference(s)