Pip^tm1Myal
Targeted Allele Detail

Summary

• Symbol: Pip^tm1Myal
• Name: prolactin induced protein; targeted mutation 1, Yvonne Myal
• MGI ID: MGI:5516489
• Synonyms: mSMGP
• Gene: Pip Location: Chr6:41824483-41828999 bp, + strand Genetic Position: Chr6, 20.05 cM, cytoband B2
• Alliance: Pip^tm1Myal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202016
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exon 2. Western blot analysis confirmed the absence of protein expression in the saliva and tears. (J:202016)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pip Mutation: 16 strains or lines available

References

• Original: J:202016 Blanchard A, et al., Generation and initial characterization of the prolactin-inducible protein (PIP) null mouse: accompanying global changes in gene expression in the submandibular gland. Can J Physiol Pharmacol. 2009 Oct;87(10):859-72
• All: 3 reference(s)