Del(10Taar2-Taar9)1Tboz
Targeted Allele Detail

Summary

• Symbol: Del(10Taar2-Taar9)1Tboz
• Name: deletion, Chr 10, Thomas Bozza 1
• MGI ID: MGI:5517421
• Synonyms: Del1Tboz, deltaT2-9, deltaT2-9^S50
• Gene: Del(10Taar2-Taar9)1Tboz Location: Chr10:23814470-23985432 bp Genetic Position: Chr10, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202086
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd or 129S6/SvEvTac or C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(10Taar2-Taar9)1Tboz involves 17 genes/genome features (Taar2, Taar3, Taar4 ...) View all
• Mutation details: Cre-mediated recombination of Taar1^tm1Tboz and Taar9^{tm2(Olfr545)Tboz} deleted a 250 kb genetic interval containing Taar2, Taar3, Taar4, Taar5, Taar6, Taar7a, Taar7b, Taar7d, Taar7e, Taar7f, Taar8a, Taar8b, Taar8c and Taar9. No over-expression of Olfr545 is detected. (J:202086)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(10Taar2-Taar9)1Tboz Mutation: 0 strains or lines available

Notes

The original targeting vectors were electroporated into 129 or (129 x C57BL/6)F1 embryonic stem cells.

References

• Original: J:202086 Pacifico R, et al., An olfactory subsystem that mediates high-sensitivity detection of volatile amines. Cell Rep. 2012 Jul 26;2(1):76-88
• All: 4 reference(s)