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Klk6tm1Arte
Targeted Allele Detail
Summary
Symbol: Klk6tm1Arte
Name: kallikrein related-peptidase 6; targeted mutation 1, TaconicArtemis
MGI ID: MGI:5517797
Gene: Klk6  Location: Chr7:43473967-43481219 bp, + strand  Genetic Position: Chr7, 28.28 cM, cytoband B4-B5
Alliance: Klk6tm1Arte page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:201375
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ and neomycin resistance cassette replaced part of exon 3 and all of exon 4. Western blot analysis confirmed the absence of protein expression in the spinal cord. (J:201375)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Klk6 Mutation:  27 strains or lines available
References
Original:  J:201375 Murakami K, et al., In vivo analysis of kallikrein-related peptidase 6 (KLK6) function in oligodendrocyte development and the expression of myelin proteins. Neuroscience. 2013 Apr 16;236:1-11
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory