Klk6^tm1Arte
Targeted Allele Detail

Summary

• Symbol: Klk6^tm1Arte
• Name: kallikrein related-peptidase 6; targeted mutation 1, TaconicArtemis
• MGI ID: MGI:5517797
• Gene: Klk6 Location: Chr7:43473967-43481219 bp, + strand Genetic Position: Chr7, 28.28 cM, cytoband B4-B5
• Alliance: Klk6^tm1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:201375
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ and neomycin resistance cassette replaced part of exon 3 and all of exon 4. Western blot analysis confirmed the absence of protein expression in the spinal cord. (J:201375)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klk6 Mutation: 27 strains or lines available

References

• Original: J:201375 Murakami K, et al., In vivo analysis of kallikrein-related peptidase 6 (KLK6) function in oligodendrocyte development and the expression of myelin proteins. Neuroscience. 2013 Apr 16;236:1-11
• All: 4 reference(s)