Adipor1^tm1.1Kry
Targeted Allele Detail

Summary

• Symbol: Adipor1^tm1.1Kry
• Name: adiponectin receptor 1; targeted mutation 1.1, Gerard Karsenty
• MGI ID: MGI:5519975
• Synonyms: AdipoR1^fl
• Gene: Adipor1 Location: Chr1:134343116-134361089 bp, + strand Genetic Position: Chr1, 58.22 cM, cytoband E4
• Alliance: Adipor1^tm1.1Kry page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199264
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. A floxed neomycin resistance cassette was inserted downstream of exon 4. Cre-mediated recombination removed the neomycin resistance cassette and left exons 2 through 4 floxed. (J:199264)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adipor1 Mutation: 45 strains or lines available

References

• Original: J:199264 Kajimura D, et al., Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1. Cell Metab. 2013 Jun 4;17(6):901-15
• All: 1 reference(s)