Lin28b^tm2.1Gqda
Targeted Allele Detail

Summary

• Symbol: Lin28b^tm2.1Gqda
• Name: lin-28 homolog B; targeted mutation 2.1, George Q Daley
• MGI ID: MGI:5520057
• Gene: Lin28b Location: Chr10:45252713-45362410 bp, - strand Genetic Position: Chr10, 23.5 cM
• Alliance: Lin28b^tm2.1Gqda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT flanked neo cassette with a 5' loxP site was inserted downstream of exon 2 via homologous recombination. FLP-mediated recombination removed the neomycin cassette. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lin28b Mutation: 23 strains or lines available

Notes

The targeting vector used to generate this allele was co-injected with the targeting vector used to generate Lin28a^tm2.1Gqda.

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 5 reference(s)