Ces4a^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Ces4a^{tm1.1(KOMP)Vlcg}
• Name: carboxylesterase 4A; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5520174
• Gene: Ces4a Location: Chr8:105858432-105876741 bp, + strand Genetic Position: Chr8, 53.04 cM
• Alliance: Ces4a^{tm1.1(KOMP)Vlcg} page
• IMPC: Ces4a gene page

Mutation origin

• Mutant Cell Line: 15497A-A12
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 17610bp between positions 107655876-107673485 of Chromosome 8 (Genome Build37), and subsequent Cre-mediated excision deleted the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ces4a Mutation: 42 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)