Prss37^tm1Zgwg
Targeted Allele Detail

Summary

• Symbol: Prss37^tm1Zgwg
• Name: serine protease 37; targeted mutation 1, Zhugang Wang
• MGI ID: MGI:5520954
• Gene: Prss37 Location: Chr6:40491757-40496418 bp, - strand Genetic Position: Chr6, 18.82 cM, cytoband B2
• Alliance: Prss37^tm1Zgwg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202066
• Parent Cell Line: PRX-129S6 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 3 and 4. Western blot analysis confirmed the absence of protein expression in the testis. (J:202066)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prss37 Mutation: 17 strains or lines available

References

• Original: J:202066 Shen C, et al., Prss37 is required for male fertility in the mouse. Biol Reprod. 2013 May;88(5):123
• All: 1 reference(s)