Clstn3^tm1.1Amcr
Targeted Allele Detail

Summary

• Symbol: Clstn3^tm1.1Amcr
• Name: calsyntenin 3; targeted mutation 1.1, Ann Marie Craig
• MGI ID: MGI:5521290
• Synonyms: Clstn3-
• Gene: Clstn3 Location: Chr6:124407715-124441743 bp, - strand Genetic Position: Chr6, 59.15 cM
• Alliance: Clstn3^tm1.1Amcr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:201987
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre and Flp recombinase mediated recombination removed exon 2, 3 and neo cassette. Immunoflorescence in brain sections and western blot analysis of whole brain homogenates confirmed the absence of expression in homozygous mice. (J:201987)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Clstn3 Mutation: 66 strains or lines available

References

• Original: J:201987 Pettem KL, et al., The Specific alpha-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development. Neuron. 2013 Oct 2;80(1):113-28
• All: 1 reference(s)