Selenbp1^tm1Hyama
Targeted Allele Detail

Summary

• Symbol: Selenbp1^tm1Hyama
• Name: selenium binding protein 1; targeted mutation 1, Hideyuki Yamada
• MGI ID: MGI:5521488
• Gene: Selenbp1 Location: Chr3:94840394-94852069 bp, + strand Genetic Position: Chr3, 40.74 cM
• Alliance: Selenbp1^tm1Hyama page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202420
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced the sequence from the middle of exon 2 through the middle of exon 12. RT-PCR confirmed the absence of protein expression in the liver, kidney, testis, stomach, intestine, brain, ovary and uterus. (J:202420)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Selenbp1 Mutation: 30 strains or lines available

References

• Original: J:202420 Tsujimoto S, et al., Selenium-binding protein 1: its physiological function, dependence on aryl hydrocarbon receptors, and role in wasting syndrome by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochim Biophys Acta. 2013 Jun;1830(6):3616-24
• All: 1 reference(s)