Otulin^m8Sapc
Chemically induced Allele Detail

Summary

• Symbol: Otulin^m8Sapc
• Name: OTU deubiquitinase with linear linkage specificity; mutation 8, Sabine Cordes
• MGI ID: MGI:5521504
• Synonyms: Gum^D336E
• Gene: Otulin Location: Chr15:27606005-27630793 bp, - strand Genetic Position: Chr15, 10.31 cM
• Alliance: Otulin^m8Sapc page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This allele was identified by screening a bank of cryopreserved sperm and genomic DNA of G1 male progeny from an ENU Mutagenesis project (http://www.brc.riken.jp/lab/gsc/mouse/). A T to A transversion en exon 7 results in replacement of Aspartic Acid at codon 336 with Glutamic Acid. (J:197674)

Expression

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Otulin Mutation: 24 strains or lines available

References

• Original: J:197674 Rivkin E, et al., The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature. 2013 Jun 20;498(7454):318-24
• All: 1 reference(s)