Tg(tetO-RNAi:Trp53)ASlowe
Transgene Detail

Summary

• Symbol: Tg(tetO-RNAi:Trp53)ASlowe
• Name: transgene insertion A, Scott W Lowe
• MGI ID: MGI:5521542
• Synonyms: TRE-p53.1224
• Transgene: Tg(tetO-RNAi:Trp53)ASlowe Location: unknown
• Alliance: Tg(tetO-RNAi:Trp53)ASlowe page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Knockdown)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-RNAi:Trp53)ASlowe involves 1 genes/genome features (Trp53) View all
• Mutation details: The tet-responsive TRE-CMV promoter drives the inducible expression of a microRNA-based short hairpin RNA targeting the mouse tumor suppressor Trp53 (referred to as p53.1224). (J:123006)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:123006 Dickins RA, et al., Tissue-specific and reversible RNA interference in transgenic mice. Nat Genet. 2007 Jul;39(7):914-21
• All: 4 reference(s)