Tg(LANA,vFLIP,vCYC)801Dtmr
Transgene Detail

Summary

• Symbol: Tg(LANA,vFLIP,vCYC)801Dtmr
• Name: transgene insertion 801, Dirk Dittmer
• MGI ID: MGI:5522554
• Transgene: Tg(LANA,vFLIP,vCYC)801Dtmr Location: unknown
• Alliance: Tg(LANA,vFLIP,vCYC)801Dtmr page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene fragment encompassing LANA, vCYC, vFLIP, KSHV miRNAs, and K12 of the KSHV latency locus was isolated from pDD801 and injected into fertilized embryos. Three founder lines were produced. (J:196403)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:196403 Sin SH, et al., Viral latency locus augments B-cell response in vivo to induce chronic marginal zone enlargement, plasma cell hyperplasia, and lymphoma. Blood. 2013 Apr 11;121(15):2952-63
• All: 2 reference(s)