Cenpu^tm1Hluo
Targeted Allele Detail

Summary

• Symbol: Cenpu^tm1Hluo
• Name: centromere protein U; targeted mutation 1, Hongyu Luo
• MGI ID: MGI:5522669
• Synonyms: MLF1-IP^-
• Gene: Cenpu Location: Chr8:47005063-47033042 bp, + strand Genetic Position: Chr8, 26.38 cM, cytoband B2
• Alliance: Cenpu^tm1Hluo page

Small size and hypocellular and disorganized epiblast tissue of Cenpu^tm1Hluo/Cenpu^tm1Hluo embryos

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202158
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A neomycin resistance cassette replaced exon 1. RT-PCR confirmed the absence of transcript expression in embryos. (J:202158)

Generation of the Cenpu^tm1Hluo allele

Expression

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cenpu Mutation: 19 strains or lines available

References

• Original: J:202158 Wang X, et al., Investigation of tissue-specific expression and functions of MLF1-IP during development and in the immune system. PLoS One. 2013;8(5):e63783
• All: 1 reference(s)