Bcl11b^m1Jpk
Chemically induced Allele Detail

Summary

• Symbol: Bcl11b^m1Jpk
• Name: B cell leukemia/lymphoma 11B; mutation 1, Japan Kominami
• MGI ID: MGI:5522760
• Synonyms: Bcl11b^m, Bcl11b^Rgsc01891, Bcl11b^S826G
• Gene: Bcl11b Location: Chr12:107876662-107969861 bp, - strand Genetic Position: Chr12, 59.1 cM, cytoband F1
• Alliance: Bcl11b^m1Jpk page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a point mutation that resulted in the amino acid substitution of glycine for serine at position 826 (S826G). This allele is hypomorphic. (J:199312)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl11b Mutation: 46 strains or lines available

References

• Original: J:199312 Katsuragi Y, et al., Bcl11b transcription factor plays a role in the maintenance of the ameloblast-progenitors in mouse adult maxillary incisors. Mech Dev. 2013 Sep-Oct;130(9-10):482-92
• All: 3 reference(s)