Zbtb16^tm1Geno
Targeted Allele Detail

Summary

• Symbol: Zbtb16^tm1Geno
• Name: zinc finger and BTB domain containing 16; targeted mutation 1, Genoway
• MGI ID: MGI:5522866
• Synonyms: PLZF^OFF
• Gene: Zbtb16 Location: Chr9:48565597-48747522 bp, - strand Genetic Position: Chr9, 26.47 cM
• Alliance: Zbtb16^tm1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199097
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Constitutively active)
• Mutation: Not Specified
• Mutation details: This allele contains a loss-of-function mutation that produces a protein that lacks DNA binding activity. (J:199097)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb16 Mutation: 30 strains or lines available

References

• Original: J:199097 Puszyk W, et al., The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells. EMBO J. 2013 Jul 3;32(13):1941-52
• All: 1 reference(s)