Nr2f1^tm2.1Mist
Targeted Allele Detail

Summary

• Symbol: Nr2f1^tm2.1Mist
• Name: nuclear receptor subfamily 2, group F, member 1; targeted mutation 2.1, Michele Studer
• MGI ID: MGI:5523158
• Synonyms: COUP-TF1^fl, COUP-TFI^flox
• Gene: Nr2f1 Location: Chr13:78337090-78346954 bp, - strand Genetic Position: Chr13, 41.38 cM
• Alliance: Nr2f1^tm2.1Mist page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:127387
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and a floxed neomycin resistance cassette was inserted downstream of exon 3. Cre-mediated recombination removed the neomycin resistance cassette. (J:127387)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr2f1 Mutation: 25 strains or lines available

References

• Original: J:127387 Armentano M, et al., COUP-TFI regulates the balance of cortical patterning between frontal/motor and sensory areas. Nat Neurosci. 2007 Oct;10(10):1277-86
• All: 9 reference(s)