Sptlc2^tm1Yhir
Targeted Allele Detail

Summary

• Symbol: Sptlc2^tm1Yhir
• Name: serine palmitoyltransferase, long chain base subunit 2; targeted mutation 1, Yoshio Hirabayashi
• MGI ID: MGI:5523495
• Synonyms: Sptlc2 flox
• Gene: Sptlc2 Location: Chr12:87351832-87435129 bp, - strand Genetic Position: Chr12, 41.52 cM, cytoband E
• Alliance: Sptlc2^tm1Yhir page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202954
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A floxed allele was generated. No details provided.

Disease models

Expression

In Structures Affected by this Mutation:

15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sptlc2 Mutation: 171 strains or lines available

References

• Original: J:202954 Ohta E, et al., Analysis of development of lesions in mice with serine palmitoyltransferase (SPT) deficiency -Sptlc2 conditional knockout mice-. Exp Anim. 2009 Oct;58(5):515-24
• All: 4 reference(s)