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Igf2bp1tm1Vssp
Targeted Allele Detail
Summary
Symbol: Igf2bp1tm1Vssp
Name: insulin-like growth factor 2 mRNA binding protein 1; targeted mutation 1, Vladimir S Spiegelman
MGI ID: MGI:5523789
Synonyms: Imp1-loxP
Gene: Igf2bp1  Location: Chr11:95847989-95896766 bp, - strand  Genetic Position: Chr11, 59.08 cM
Alliance: Igf2bp1tm1Vssp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202774
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 5. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 6. (J:202774)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igf2bp1 Mutation:  103 strains or lines available
References
Original:  J:202774 Hamilton KE, et al., IMP1 promotes tumor growth, dissemination and a tumor-initiating cell phenotype in colorectal cancer cell xenografts. Carcinogenesis. 2013 Nov;34(11):2647-54
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory