Tbx20^tm2Ccai
Targeted Allele Detail

Summary

• Symbol: Tbx20^tm2Ccai
• Name: T-box 20; targeted mutation 2, Chen-Leng Cai
• MGI ID: MGI:5523914
• Synonyms: Tbx20^V5-Tbx20-Avi
• Gene: Tbx20 Location: Chr9:24632108-24685580 bp, - strand Genetic Position: Chr9, 10.25 cM
• Alliance: Tbx20^tm2Ccai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:198628
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A Tbx20 cDNA fused to sequence for V5 epitope tag at the 5' end and the Avi peptide at the 3' end was inserted in exon 1 replacing the coding sequence. The Avi peptide facilitates biotinylation. (J:198628)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx20 Mutation: 36 strains or lines available

References

• Original: J:198628 Cai X, et al., Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis. Development. 2013 Aug;140(15):3176-87
• All: 2 reference(s)