Del(13)1Mgld
Targeted Allele Detail

Summary

• Symbol: Del(13)1Mgld
• Name: deletion, Chr 13, Michael N Gould
• MGI ID: MGI:5524113
• Synonyms: Del1Mgld, MD
• Gene: Del(13)1Mgld Location: unknown Genetic Position: Chr13, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199158
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intergenic deletion Mutation details: Cre-mediated recombination between MICER clones MHPP256h04 (13:78,918,316; MM9) and MHPN5k06 (13:79,454,030; MM9) that restores a functional Hprt gene and generated a megadeletion (MD) of 535 Mb containing the orthologous region to the rat mammary carcinoma susceptibility locus Mcs1a. (J:199158)

Generation of a chromosome 13 deletion, Del(13)1Mgld

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(13)1Mgld Mutation: 0 strains or lines available

References

• Original: J:199158 Smits BM, et al., The gene desert mammary carcinoma susceptibility locus mcs1a regulates nr2f1 modifying mammary epithelial cell differentiation and proliferation. PLoS Genet. 2013 Jun;9(6):e1003549
• All: 2 reference(s)