Nrg1^tm4Cbm
Targeted Allele Detail

Summary

• Symbol: Nrg1^tm4Cbm
• Name: neuregulin 1; targeted mutation 4, Carmen Birchmeier
• MGI ID: MGI:5524247
• Synonyms: IgNrg1^flox
• Gene: Nrg1 Location: Chr8:32299493-33381858 bp, - strand Genetic Position: Chr8, 18.75 cM
• Alliance: Nrg1^tm4Cbm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199150
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 4, which encodes part of the Ig-like domain, was floxed. (J:199150)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrg1 Mutation: 54 strains or lines available

References

• Original: J:199150 Cheret C, et al., Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles. EMBO J. 2013 Jul 17;32(14):2015-28
• All: 2 reference(s)