Gt(ROSA)26Sor^{tm1.1(Sstr3/GFP)Bky}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(Sstr3/GFP)Bky}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Bradley K Yoder
• MGI ID: MGI:5524282
• Synonyms: Cilia^GFP-ON
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(Sstr3/GFP)Bky} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199240
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1.1(Sstr3/GFP)Bky} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sstr3 (MGI:98329)

• Mutation details: The targeting construct introduced into the locus a splice acceptor, floxed neomycin resistance/STOP cassette, fusion of the cilia localizing cDNA and GFP flanked by attB and a polyadenylation sequence. Cre-mediated recombination removed the neomycin resistance/STOP cassette. (J:199240)

Expression

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:199240 O'Connor AK, et al., An inducible CiliaGFP mouse model for in vivo visualization and analysis of cilia in live tissue. Cilia. 2013;2(1):8
• All: 3 reference(s)