Ddx10^m1J
Spontaneous Allele Detail

Summary

• Symbol: Ddx10^m1J
• Name: DEAD box helicase 10; mutation 1 Jackson
• MGI ID: MGI:5526028
• Gene: Ddx10 Location: Chr9:53009935-53159353 bp, - strand Genetic Position: Chr9, 29.12 cM
• Alliance: Ddx10^m1J page

Mutation origin

• Strain of Origin: (C57BL/6J x 129S1/SvImJ)F2/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: The molecular mutation is a G-to-T base pair change on chromosome 9 at 53,157,219 (GRCm38/mm10). This single base pair change results in a p.D736E mutation, changing a highly conserved amino acid in the encoded protein. (J:223062)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ddx10 Mutation: 48 strains or lines available

References

• Original: J:222308 Fairfield H, et al., Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. Genome Res. 2015 Jul;25(7):948-57
• All: 2 reference(s)