Gt(ROSA)26Sor^{tm1(CAG-Etv2,-GFP)Hkata}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Etv2,-GFP)Hkata}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Hiroshi Kataoka
• MGI ID: MGI:5527402
• Synonyms: CAG-floxSTOP-etv2-frtGFP, ROSA-Etv2
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Etv2,-GFP)Hkata} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203163
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(CAG-Etv2,-GFP)Hkata} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Etv2 (MGI:99253)

• Mutation details: The targeting construct inserted into the locus a CAG promoter, floxed neomycin/STOP cassette, mouse cDNA, IRES, GFP and polyadenylation sequence. (J:203163)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:203163 Hayashi M, et al., Endothelialization and altered hematopoiesis by persistent Etv2 expression in mice. Exp Hematol. 2012 Sep;40(9):738-750.e11
• All: 1 reference(s)