Tg(Mbp-Cadm4*)#Pele
Transgene Detail
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| Symbol: |
Tg(Mbp-Cadm4*)#Pele |
| Name: |
transgene insertion, Elior Peles |
| MGI ID: |
MGI:5528809 |
| Synonyms: |
Tg(mbp-Cadm4dCT) |
| Transgene: |
Tg(Mbp-Cadm4*)#Pele Location: unknown
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| Alliance: |
Tg(Mbp-Cadm4*)#Pele page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Dominant negative, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The myelin basic protein promoter drives expression of a myc-tagged mutant Cadm4 transcript lacking the entire cytoplasmic domain. This functions as a dominant negative mutation. Western blot analysis demonstrated strong expression in the sciatic nerve.
(J:199632)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:199632 Golan N, et al., Genetic deletion of Cadm4 results in myelin abnormalities resembling charcot-marie-tooth neuropathy. J Neurosci. 2013 Jul 3;33(27):10950-61 |
| All: |
2 reference(s) |
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Analysis Tools
