Gfy^tm1Yyos
Targeted Allele Detail

Summary

• Symbol: Gfy^tm1Yyos
• Name: golgi-associated olfactory signaling regulator; targeted mutation 1, Yoshihiro Yoshihara
• MGI ID: MGI:5529101
• Gene: Gfy Location: Chr7:44825773-44828993 bp, - strand Genetic Position: Chr7, Syntenic
• Alliance: Gfy^tm1Yyos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199864
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An inverse orientation neo cassette replaced exons 1, 2 and part of exon 3. Western blot and immunohistochemical analysis confirmed the absence of protein expression in the olfactory epithelium from homozygous mice. (J:199864)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gfy Mutation: 23 strains or lines available

References

• Original: J:199864 Kaneko-Goto T, et al., Goofy coordinates the acuity of olfactory signaling. J Neurosci. 2013 Aug 7;33(32):12987-96
• All: 1 reference(s)