Clec7a^tm1.1Bpip
Targeted Allele Detail

Summary

• Symbol: Clec7a^tm1.1Bpip
• Name: C-type lectin domain family 7, member a; targeted mutation 1.1, Bernard Pipy
• MGI ID: MGI:5529120
• Synonyms: Dectin-1^L2
• Gene: Clec7a Location: Chr6:129438554-129449742 bp, - strand Genetic Position: Chr6, 63.34 cM, cytoband F3
• Alliance: Clec7a^tm1.1Bpip page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203908
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 3 through 6 were floxed. Flp-mediated recombination removed the FRT-flanked selection cassette. (J:203908)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clec7a Mutation: 24 strains or lines available

References

• Original: J:203908 Gales A, et al., PPARgamma controls Dectin-1 expression required for host antifungal defense against Candida albicans. PLoS Pathog. 2010 Jan;6(1):e1000714
• All: 4 reference(s)