Tenm2^tm1Cal
Targeted Allele Detail

Summary

• Symbol: Tenm2^tm1Cal
• Name: teneurin transmembrane protein 2; targeted mutation 1, Catherine A Leamey
• MGI ID: MGI:5529622
• Gene: Tenm2 Location: Chr11:35897483-37126791 bp, - strand Genetic Position: Chr11, 21.96 cM
• Alliance: Tenm2^tm1Cal page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199791
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 5 was disrupted through insertion of a neo cassette. Western blot analysis confirms knockdown of protein expression in homozygous mice. (J:199791)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tenm2 Mutation: 133 strains or lines available

References

• Original: J:199791 Young TR, et al., Ten-m2 Is Required for the Generation of Binocular Visual Circuits. J Neurosci. 2013 Jul 24;33(30):12490-509
• All: 1 reference(s)