Aurka^{tm1b(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Aurka^{tm1b(EUCOMM)Hmgu}
• Name: aurora kinase A; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5529637
• Gene: Aurka Location: Chr2:172198110-172212455 bp, - strand Genetic Position: Chr2, 94.84 cM
• Alliance: Aurka^{tm1b(EUCOMM)Hmgu} page
• IMPC: Aurka gene page

Mutation origin

• Mutant Cell Line: HEPD0510_4_F05
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: JM8.N4 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 41398bp between positions 113718004-113759401 of Chromosome 13 (Genome Build37), and subsequent Cre-mediated excision removed the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:	26 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Aurka Mutation: 40 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 4 reference(s)