Ass1tm1.2Ekoe
Targeted Allele Detail
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Symbol: |
Ass1tm1.2Ekoe |
Name: |
argininosuccinate synthetase 1; targeted mutation 1.2, Eleonore Kohler |
MGI ID: |
MGI:5529836 |
Gene: |
Ass1 Location: Chr2:31360282-31410682 bp, + strand Genetic Position: Chr2, 21.81 cM
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Alliance: |
Ass1tm1.2Ekoe page
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Germline Transmission: |
Earliest citation of germline transmission:
J:203474
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Parent Cell Line: |
IB10/E14IB10 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 13. An additional loxP site was inserted downstream of exon 13. Flpe-mediated recombination removed the neomycin resistance cassette. Cre-mediated recombination removed exon 13.
(J:203474)
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Generation of the Ass1tm1.1Ekoe and Ass1tm1.2Ekoe alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ass1 Mutation: |
58 strains or lines available
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Original: |
J:203474 Marion V, et al., Hepatic adaptation compensates inactivation of intestinal arginine biosynthesis in suckling mice. PLoS One. 2013;8(6):e67021 |
All: |
1 reference(s) |
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