Zbtb16^{tm1.1(EGFP/cre)Aben}
Targeted Allele Detail

Summary

• Symbol: Zbtb16^{tm1.1(EGFP/cre)Aben}
• Name: zinc finger and BTB domain containing 16; targeted mutation 1.1, Albert Bendelac
• MGI ID: MGI:5532503
• Synonyms: PLZF^GFPcre, Zbtb16^{tm1.1(EGFPcre)Aben}
• Gene: Zbtb16 Location: Chr9:48565597-48747522 bp, - strand Genetic Position: Chr9, 26.47 cM
• Alliance: Zbtb16^{tm1.1(EGFP/cre)Aben} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:204428
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Zbtb16^{tm1.1(EGFP/cre)Aben} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Zbtb16 (MGI:103222)

• Mutation details: An IRES linked to an EGFP-cre fusion protein and an FRT-flanked neomycin resistance cassette were introduced immediately after the Zbtb16 (Plzf) stop codon (in exon 7) via homologous recombination in C57BL/6J-derived embryonic stem (ES) cells. Mice were bred to ACTB-FLPe animals to excise the neomycin cassette and create the PLZF allele. (J:204428, J:205609)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Zbtb16 (mouse) Summary of all recombinase alleles driven by Zbtb16. Alliance mouse Zbtb16 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zbtb16 Mutation: 30 strains or lines available

References

• Original: J:204428 Bendelac A, A cre knockin allele of the Zbtb16 gene. MGI Direct Data Submission. 2014
• All: 25 reference(s)