Msx2^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Msx2^m1Btlr
• Name: msh homeobox 2; mutation 1, Bruce Beutler
• MGI ID: MGI:5532713
• Synonyms: duke
• Gene: Msx2 Location: Chr13:53620917-53626816 bp, - strand Genetic Position: Chr13, 27.84 cM
• Alliance: Msx2^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G to T transversion at base pair 53468395 (v38) on Chromosome 13, equivalent to base pair 388435 in the GenBank genomic region NC_000079. The mutation corresponds to residue 648 in the NM_013601 mRNA sequence in exon 2 of 2 total exons. The mutation results in an arginine (R) to leucine (L) substitution at residue 193 (R193L). (J:204501)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Msx2 Mutation: 23 strains or lines available

References

• Original: J:204501 Weatherly J, et al., Direct data submission for Mutagenetix entry for duke. MGI Direct Data Submission. 2014
• All: 1 reference(s)