Izumo1r^tm1.1Salb
Targeted Allele Detail

Summary

• Symbol: Izumo1r^tm1.1Salb
• Name: IZUMO1 receptor, JUNO; targeted mutation 1.1, J Michael Salbaum
• MGI ID: MGI:5538512
• Gene: Izumo1r Location: Chr9:14797110-14815245 bp, - strand Genetic Position: Chr9, 4.42 cM
• Alliance: Izumo1r^tm1.1Salb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202519
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first two coding exons were flanked by loxP sites and the second loxP site was followed by a neomycin resistance gene and a third loxP site. Properly targeted mice were crossed to mice expressing cre in oocytes to excise the selection cassette and the two floxed exons. (J:202519)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Izumo1r Mutation: 23 strains or lines available

References

• Original: J:202519 Salbaum JM, et al., Mutation at the folate receptor 4 locus modulates gene expression profiles in the mouse uterus in response to periconceptional folate supplementation. Biochim Biophys Acta. 2013 Oct;1832(10):1653-61
• All: 3 reference(s)