Pgap3^tm1.1Ymra
Targeted Allele Detail

Summary

• Symbol: Pgap3^tm1.1Ymra
• Name: post-GPI attachment to proteins 3; targeted mutation 1.1, Yoshiko Murakami
• MGI ID: MGI:5538630
• Gene: Pgap3 Location: Chr11:98279503-98291316 bp, - strand Genetic Position: Chr11, 61.75 cM
• Alliance: Pgap3^tm1.1Ymra page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181221
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 7. A neomycin resistance cassette with a 3' loxP site was inserted downstream of the coding sequence in the 3' UTR in exon 8. Cre-mediated recombination removed the coding sequence of exon 7 and 8. (J:181221)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pgap3 Mutation: 28 strains or lines available

References

• Original: J:181221 Murakami H, et al., Enhanced response of T lymphocytes from Pgap3 knockout mouse: Insight into roles of fatty acid remodeling of GPI anchored proteins. Biochem Biophys Res Commun. 2012 Jan 27;417(4):1235-41
• All: 2 reference(s)