Tg(Cdx2-cre)R337Npln
Transgene Detail

Summary

• Symbol: Tg(Cdx2-cre)R337Npln
• Name: transgene insertion R337, Nicolas Pilon
• MGI ID: MGI:5543474
• Synonyms: Cdx2NSE-Cre
• Transgene: Tg(Cdx2-cre)R337Npln Location: unknown
• Alliance: Tg(Cdx2-cre)R337Npln page

Transgene origin

• Strain of Origin: C57BL/6 x C3H

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Cdx2-cre)R337Npln expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cdx2 (MGI:88361)

• Mutation details: An 852 bp fragment of intron 1 of the mouse Cdx2 gene containing a neural specific enhancer was cloned upstream of a cre recombinase expression cassette. The cre cassette contains an Hsp68 minimal promoter, the cre recombinase open reading frame and the SV40 polyadenylation sequences. This construct was injected into (C57BL/6 x C3H) oocytes. Thirteen F0 founders were obtained with 8 testing positive for cre activity. A single male, R337, was bred to a wild type B6 female. (J:204467)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cdx2 (mouse) Summary of all recombinase alleles driven by Cdx2. Comparative matrix view of recombinase activities Alliance mouse Cdx2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:204467 Coutaud B, et al., Characterization of a novel transgenic mouse line expressing Cre recombinase under the control of the Cdx2 neural specific enhancer. Genesis. 2013 Nov;51(11):777-84
• All: 3 reference(s)