Gjd3^tm2.1Kwi
Targeted Allele Detail

Summary

• Symbol: Gjd3^tm2.1Kwi
• Name: gap junction protein, delta 3; targeted mutation 2.1, Klaus Willecke
• MGI ID: MGI:5544288
• Synonyms: Cx30.2KO (YFP)
• Gene: Gjd3 Location: Chr11:98873006-98873842 bp, - strand Genetic Position: Chr11, 62.89 cM
• Alliance: Gjd3^tm2.1Kwi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205110
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence was replaced with an FRT-flanked neomycin resistance cassette and EYFP. Flp-mediated recombination removed the neomycin resistance cassette. (J:205110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gjd3 Mutation: 13 strains or lines available

References

• Original: J:205110 Frank M, et al., Connexin45 provides optimal atrioventricular nodal conduction in the adult mouse heart. Circ Res. 2012 Dec 7;111(12):1528-38
• All: 1 reference(s)