Tg(RHO-cre)1Qliu
Transgene Detail

Summary

• Symbol: Tg(RHO-cre)1Qliu
• Name: transgene insertion 1, Qinghuai Liu
• MGI ID: MGI:5546625
• Synonyms: Rho-Cre
• Transgene: Tg(RHO-cre)1Qliu Location: unknown
• Alliance: Tg(RHO-cre)1Qliu page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(RHO-cre)1Qliu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  cattle	RHO (509933)

• Mutation details: A vector containing the bovine rhodopsin promoter (RHO) and cre recombinase with a nuclear localization signal sequence was used for pronuclear injection of C57BL/6 x SJL oocytes. Nine transgenic founders were generated. RT-PCR analysis showed only retina-specific expression with no other positive tissue. The mice were crossed with Rosa26R-lacZ reporter animals to assess cre activity and specificity, with recombination (lacZ staining) detected specifically in rod photoreceptors. (J:205526)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	RHO (cattle) Summary of all recombinase alleles driven by RHO. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:205526 Ding Y, et al., Retina-specific gene excision by targeted expression of Cre recombinase. Biochem Biophys Res Commun. 2013 Nov 29;441(4):777-81
• All: 1 reference(s)