Tnfrsf21^tm1Arte
Targeted Allele Detail

Summary

• Symbol: Tnfrsf21^tm1Arte
• Name: tumor necrosis factor receptor superfamily, member 21; targeted mutation 1, TaconicArtemis
• MGI ID: MGI:5546637
• Gene: Tnfrsf21 Location: Chr17:43327446-43400079 bp, + strand Genetic Position: Chr17, 19.69 cM, cytoband C
• Alliance: Tnfrsf21^tm1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205651
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked positive selection cassette replaced exons 2 and 3. Western blot analysis confirmed the absence of protein expression in the brain at P15 and P30. (J:205651)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfrsf21 Mutation: 61 strains or lines available

References

• Original: J:205651 Mi S, et al., Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination. Nat Med. 2011 Jul;17(7):816-21
• All: 3 reference(s)