Carmil2^bas
Chemically induced Allele Detail

Summary

• Symbol: Carmil2^bas
• Name: capping protein regulator and myosin 1 linker 2; basilic
• MGI ID: MGI:5547539
• Gene: Carmil2 Location: Chr8:106412906-106424819 bp, + strand Genetic Position: Chr8, 53.04 cM
• Alliance: Carmil2^bas page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• ENU mutagenesis induced a T to C point mutation in exon 16. (J:205441)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Carmil2 Mutation: 39 strains or lines available

Notes

ENU mutagenesis was conducted on Lat^tm8Mal mice constructed in Bruce-4 ES cells.

References

• Original: J:205441 Liang Y, et al., The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells. Nat Immunol. 2013 Aug;14(8):858-66
• All: 1 reference(s)