Gt(ROSA)26Sor^{tm1.1(Wls/YFP)Mbtr}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(Wls/YFP)Mbtr}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Michael Boutros
• MGI ID: MGI:5547722
• Synonyms: ROSA26:Evi-YFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(Wls/YFP)Mbtr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202499
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1.1(Wls/YFP)Mbtr} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Wls (MGI:1915401)

• Mutation details: A targeting construct introduced into the locus a floxed beta-geo cassette and a C-terminal fusion of the mouse cDNA and YFP. Cre-mediated recombination removed the beta-geo cassette and allowed for expression of the fusion product. (J:202499)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:202499 Augustin I, et al., Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis. J Exp Med. 2013 Aug 26;210(9):1761-77
• All: 1 reference(s)