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Gt(ROSA)26Sortm1.1(Wls/YFP)Mbtr
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1.1(Wls/YFP)Mbtr
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Michael Boutros
MGI ID: MGI:5547722
Synonyms: ROSA26:Evi-YFP
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1.1(Wls/YFP)Mbtr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:202499
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1.1(Wls/YFP)Mbtr expresses 1 gene
 
Mutation detailsA targeting construct introduced into the locus a floxed beta-geo cassette and a C-terminal fusion of the mouse cDNA and YFP. Cre-mediated recombination removed the beta-geo cassette and allowed for expression of the fusion product. (J:202499)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  992 strains or lines available
References
Original:  J:202499 Augustin I, et al., Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis. J Exp Med. 2013 Aug 26;210(9):1761-77
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory