Slc6a2^tm1.1Hhg
Targeted Allele Detail

Summary

• Symbol: Slc6a2^tm1.1Hhg
• Name: solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2; targeted mutation 1.1, Haihua Gu
• MGI ID: MGI:5547831
• Synonyms: NET-CI
• Gene: Slc6a2 Location: Chr8:93687100-93728295 bp, + strand Genetic Position: Chr8, 44.99 cM
• Alliance: Slc6a2^tm1.1Hhg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: The targeting construct was designed to insert a loxP-flanked neomycin (neo) resistance cassette downstream of exon 2. The double mutation, F101C/A105G, was introduced in exon 2 and a third mutation, N153T, was introduced into exon 3. Cre-mediated recombination removed the floxed neo cassette. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc6a2 Mutation: 35 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)