Atf3^tm1.1Hai
Targeted Allele Detail

Summary

• Symbol: Atf3^tm1.1Hai
• Name: activating transcription factor 3; targeted mutation 1.1, Tsonwin Hai
• MGI ID: MGI:5547956
• Synonyms: Atf3^f
• Gene: Atf3 Location: Chr1:190902493-190915530 bp, - strand Genetic Position: Chr1, 96.28 cM, cytoband H6
• Alliance: Atf3^tm1.1Hai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:201626
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon B. An additional loxP site was inserted downstream of exon B. Flp-mediated recombination removed the neomycin resistance cassette and left exon B floxed. (J:201626)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atf3 Mutation: 21 strains or lines available

References

• Original: J:201626 Wolford CC, et al., Transcription factor ATF3 links host adaptive response to breast cancer metastasis. J Clin Invest. 2013 Jul 1;123(7):2893-906
• All: 11 reference(s)