Pak1ip1^mray
Chemically induced Allele Detail

Summary

• Symbol: Pak1ip1^mray
• Name: PAK1 interacting protein 1; manta-ray
• MGI ID: MGI:5548169
• Gene: Pak1ip1 Location: Chr13:41154499-41166491 bp, + strand Genetic Position: Chr13, 20.23 cM
• Alliance: Pak1ip1^mray page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a C to T point mutation that results in the amino acid substitution of tyrosine for histidine at position 122 (H122Y). (J:204457)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pak1ip1 Mutation: 28 strains or lines available

References

• Original: J:204457 Ross AP, et al., A mutation in mouse Pak1ip1 causes orofacial clefting while human PAK1IP1 maps to 6p24 translocation breaking points associated with orofacial clefting. PLoS One. 2013;8(7):e69333
• All: 2 reference(s)