Ctdnep1^tm3Ryn
Targeted Allele Detail

Summary

• Symbol: Ctdnep1^tm3Ryn
• Name: CTD nuclear envelope phosphatase 1; targeted mutation 3, Ryuichi Nishinakamura
• MGI ID: MGI:5548188
• Synonyms: Dullard^flox
• Gene: Ctdnep1 Location: Chr11:69871994-69881427 bp, + strand Genetic Position: Chr11, 42.95 cM, cytoband B4
• Alliance: Ctdnep1^tm3Ryn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205755
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 4. (J:205755)

Expression

In Mice Carrying this Mutation:	16 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctdnep1 Mutation: 20 strains or lines available

References

• Original: J:205755 Sakaguchi M, et al., The phosphatase Dullard negatively regulates BMP signalling and is essential for nephron maintenance after birth. Nat Commun. 2013;4:1398
• All: 5 reference(s)