Rarres2^tm1Yktk
Targeted Allele Detail

Summary

• Symbol: Rarres2^tm1Yktk
• Name: retinoic acid receptor responder (tazarotene induced) 2; targeted mutation 1, Yutaka Takahashi
• MGI ID: MGI:5550146
• Gene: Rarres2 Location: Chr6:48546630-48549723 bp, - strand Genetic Position: Chr6, 23.55 cM
• Alliance: Rarres2^tm1Yktk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:206120
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence of exon 2 was replaced with a loxP site, lacZ gene, FRT-flanked neomycin resistance cassette, loxP site and polyadenylation sequence. Western blot analysis confirmed the absence of protein expression in the serum. (J:206120)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rarres2 Mutation: 10 strains or lines available

References

• Original: J:206120 Takahashi M, et al., Chemerin regulates beta-cell function in mice. Sci Rep. 2011;1:123
• All: 1 reference(s)