Tg(Adipoq-cre/Esr1*)1Evdr
Transgene Detail

Summary

• Symbol: Tg(Adipoq-cre/Esr1*)1Evdr
• Name: transgene insertion 1, Evan Rosen
• MGI ID: MGI:5550467
• Synonyms: Adiponectin-creER
• Transgene: Tg(Adipoq-cre/Esr1*)1Evdr Location: unknown
• Alliance: Tg(Adipoq-cre/Esr1*)1Evdr page

Transgene origin

• Strain of Origin: 129

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Adipoq-cre/Esr1*)1Evdr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Adipoq (MGI:106675)

• Mutation details: To generate the Adipoq-cre/Esr1 BAC transgenic mice, the 245 kb RP23-90G21 bacterial artificial chromosome (BAC) containing at least five mouse genes was modified by replacing the starting ATG and 222 bp of the adiponectin gene with the starting ATG and sequence encoding the cre/ERT, cre recombinase and an estrogen receptor 1 (mouse) fusion gene. This modified BAC transgene was microinjected into fertilized 129 mouse eggs. Founder line 1 was subsequently established. (J:206506)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Adipoq (mouse) Summary of all recombinase alleles driven by Adipoq. Alliance mouse Adipoq gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:206506 Rosen, et al., Generation of an inducible Adipoq-cre transgene. MGI Direct Data Submission. 2014
• All: 39 reference(s)