Mapt^{tm1(Sema3e)Yuyo}
Targeted Allele Detail

Summary

• Symbol: Mapt^{tm1(Sema3e)Yuyo}
• Name: microtubule-associated protein tau; targeted mutation 1, Yutaka Yoshida
• MGI ID: MGI:5550516
• Synonyms: lsl-Sema3E-iresGFP
• Gene: Mapt Location: Chr11:104122216-104222916 bp, + strand Genetic Position: Chr11, 67.79 cM, cytoband E1
• Alliance: Mapt^{tm1(Sema3e)Yuyo} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205528
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, No functional change)
• Mutation: Insertion
• A lox-stop-lox-Sema3E-ires-GFP-polyA-targeting cassette was integrated into exon 2 of the Tau locus. (J:205528)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mapt Mutation: 430 strains or lines available

References

• Original: J:205528 Fukuhara K, et al., Specificity of monosynaptic sensory-motor connections imposed by repellent Sema3E-PlexinD1 signaling. Cell Rep. 2013 Nov 14;5(3):748-58
• All: 1 reference(s)