Nme8^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Nme8^tm1.1Arte
• Name: NME/NM23 family member 8; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:5550546
• Synonyms: Sptrx-2^-
• Gene: Nme8 Location: Chr13:19829248-19881964 bp, - strand Genetic Position: Chr13, 7.0 cM, cytoband A3.3
• Alliance: Nme8^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:205172
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: The conserved WCGPC site in exon 4 was mutated to WSGPS. An FRT flanked neo-cassette was inserted downstream of exon 4 and then removed via recombinase, resulting in a single FRT site in intron 4. (J:205172)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nme8 Mutation: 40 strains or lines available

References

• Original: J:205172 Smith TB, et al., Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress. Free Radic Biol Med. 2013 Dec;65:872-81
• All: 1 reference(s)